L.B.S. LABS LTD PART
Contents
Lidocaine + Prilocaine
Indication
Local anaesthesia
Instruction
Adult: As eutectic mixture containing lidocaine base 2.5% and prilocaine base 2.5%: For minor procedures (e.g. IV cannulation or venipuncture): Apply 2.5 g over 20-25 cm2 of skin surface for at least 1 hr. For major dermal procedures involving a larger skin area: Apply 2 g per 10 cm2 of skin and allow to remain in contact with the skin for at least 2 hr. As adjunct to local infiltration anesth in genital mucous membranes: Apply 1 g per 10 cm2 of the skin surface for 15 minutes; local anaesthetic infiltration procedure should be performed immediately after removal of cream. For superficial minor surgery of genital mucous membranes in adult females: Apply 5-10 g for 5-10 minutes.
Child: Dose depends on age and wt of the child. 0-3 mth or <5 kg: Max of 1 g over no >10 cm2 of skin; leave on for no >1 hr. 3-12 mth and >5 kg: Max of 2 g over no >20 cm2 of skin; leave on for no >4 hr. 1-6 yr and >10 kg: Max of 10 g over no >100 cm2 of skin; leave on for no >4 hr. 7-12 yr and >20 kg: Max of 20 g over no >200 cm2 of skin; leave on for no >4 hr. For children >3 mth: Max total dose should be based on the patient's wt rather than the age.
Elderly: Dose reduction may be required.
Drug interaction
Increased risk of toxicity when used with drugs that are known to cause methaemoglobinaemia. Concurrent use with class III antiarrhythmics may lead to additive cardiac effects. Toxic effects may be additive when used with class I antiarrhythmics.
Malaysia
