Deskripsi
Manufacturer
Cipla
Contents
Salbutamol
Indication
Asthalin Repsules is used for treating or preventing breathing problems in patients who have asthma or certain other airway diseases. It may be used to prevent breathing problems caused by exercise. Asthalin Repsules is a sympathomimetic (beta agonist) bronchodilator. It works by relaxing the smooth muscle in the airway, which allows air to flow in and out of the lungs more easily.
Instruction
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A suitable starting dose of salbutamol by wet inhalation is 2.5 milligrams. This may be increased to 5 milligrams.
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Treatment may be repeated four times daily.
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Clinical efficacy of nebulised salbutamol in infants under 18 months is uncertain. As transient hypoxaemia may occur, supplemental oxygen therapy should be considered.
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Asthalin Nebules are intended to be used undiluted. However, if prolonged delivery time is desirable (more than 10 minutes) dilution using sterile normal saline as a diluent may be required.
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Asthalin Nebules are to be used with a nebuliser, under the direction of a physician. The solution must not be injected, or swallowed. Increasing use of beta-2agonists may be a sign of worsening asthma. Under these conditions a reassessment of the patient's therapy plan may be required and concomitant glucocorticosteroid therapy should be considered.
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Delivery of the aerosol may be by facemask, 'T' piece or via an endotracheal tube. Intermittent positive pressure ventilation may be used but is rarely necessary. When there is a risk of anoxia through hypoventilation, oxygen should be added to the inspired air.
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As there may be adverse effects associated with excessive dosing, the dosage or frequency of administration should only be increased on medical advice. As many nebulisers operate on a continuous flow basis, it is likely that nebulised drug will be released in the local environment.
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Asthalin Nebules should therefore be administered in a well ventilated room, particularly in hospitals when several patients may be using nebulisers in the same space at the same time.
Drug interaction
Asthalin HFA Repsules interact with the following medicines: airway-opening medications such as Alupent, Proventil, and Serevent; blood pressure medications known as beta blockers, including Inderal, Lopressor, and Tenormin; MAO inhibitors such as the antidepressants Marplan, Nardil, and Parnate; Tricyclic antidepressants such as Elavil and Tofranil; water pills (diuretics) such as furosemide (Lasix) and hydrochlorothiazide (HydroDIURIL). Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the effect of drugs, so consult with your doctor about how it interactions are being managed or should be managed.
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