Deskripsi
Manufacturer
Pfizer
Contents
Phenytoin Na
Indication
Dilantin is used to control seizures. It is not made to treat all types of seizures, and your doctor will determine if it is the right medication for you. Dilantin is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures.
Instruction
Use Dilantin as directed by your doctor.
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Do not take in larger or smaller amounts or for longer than recommended.
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Do not crush, chew, break, or open a capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.
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To be sure Dilantin is helping your condition, your blood may need to be tested often.
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If you miss a dose of Dilantin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Dilantin.
Drug interaction
Dilantin increases effects of coumarin anticoagulant drugs, while the anticoagulants in their turn increase blood levels of Dilantin which may aggravate risk of toxicity and hemorrhagic complications. Inform your doctor if you are taking digoxin, carbamazepine, clonazepam, corticosteroids (prednisone), cyclosporine, disopyramide, doxycycline, estrogens, felodipine, levodopa, lidocaine, methadone, mexiletine, oral contraceptives, paroxetine, quinidine, tacrolimus, theophylline, phenobarbital, and warfarin as they may decrease blood levels of Dilantin. Tricyclic antidepressants [Amitriptyline (Elavil, Endep), Desipramine (Norpramin, Pertofrane), Amoxapine (Asendin), Clomipramine (Anafranil), Imipramine (Tofranil), Nortriptyline (Pamelor, Aventyl), Doxepin (Adapin, Sinequan), Protriptyline (Vivactil), Trimipramine (Surmontil)] in large doses diminish a convulsive threshold and in small doses increase it, some of them are able to slow down metabolism of Dilantin and increase its toxicity hereby. Isonicotinic acid, certain antibiotics (levomitsetin), sulfonamides, aminasine are able to increase toxicity of Dilantin. Dilantin increases hypotention effects of diuretics and other anti-hypertension medications, strengthens action of anapryline and antiarrhythmic medications, thyroid hormone replacement drugs. Dilantin decreases activity of medications for diabetes, affects metabolism of corticosteroids and tetracycline (Vibramycin), influences absorption of diuretics (Furocemide). Dilantin may increase indices of bilirubin, cholesterol, glucose, alkaline phosphatase, liver transaminases in blood tests.
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