Manufacturer
GlaxoSmithKline
Contents
Lacidipine
Indication
Hypertension either alone or in combination with other antihypertensive agents.
Instruction
May be taken with or without food.
Drug interaction
Additive hypotensive effect w/ antihypertensive agents (eg, diuretics, β-blockers, ACE inhibitors). May increase plasma levels w/ cimetidine. Altered bioavailability w/ grapefruit juice. Reverse decreased renal plasma flow & GFR induced by cyclosporin. Concurrent use w/ CYP3A4 inhibitors & inducers.