Manufacturer
Sanofi-aventis
Contents
Insulin glargine
Indication
Diabetes mellitus
Instruction
Once daily individualized dosage.
Drug interaction
Enhanced blood-glucose-lowering effect w/ antihyperglycaemics, ACE inhibitors, disopyramide, fibrates, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates & sulfonamides. Reduced blood-glucose-lowering effect by corticosteroids, danazol, diazoxide, diuretics, glucagon, INH, oestrogens & progestogens, phenothiazine derivatives, somatropin, sympathomimetic medicinal products [eg, epinephrine (adrenaline), salbutamol, terbutaline], thyroid hormones, atypical antipsychotics (eg, clozapine & olanzapine) & protease inhibitors. Potentiated or weakened blood-glucose-lowering effect w/ β-blockers, clonidine, lithium salts or alcohol. Hypoglycemia sometimes followed by hyperglycemia w/ pentamidine. Reduced or absent signs of adrenergic counterregulation w/ sympatholytics eg, guanethidine, reserpine.
Malaysia
