Manufacturer
Bayer
Contents
Rivaroxaban
Indication
Prevention of venous thromboembolism (VTE) in adult patients undergoing elective hip or knee replacement surgery
Instruction
May be taken with or without food
Drug interaction
Reduced hepatic & renal clearance & increased systemic exposure w/ strong CYP3A4 & P-gp inhibitors (eg, azole antimycotics or HIV-PIs). Decreased plasma conc w/ CYP3A4 inducers eg, rifampicin, phenytoin, carbamazepine, phenobarb or St. John's wort. Clotting parameter tests.