Manufacturer
YSP
Contents
Gemfibrozil
Indication
YSP Brozil is used for treating high blood cholesterol and triglycerides. It is used along with an appropriate diet. YSP Brozil is an antihyperlipidemic agent. It works by lowering the blood levels of triglycerides and low-density lipoprotein (LDL) ('bad') cholesterol by reducing their production by the liver. It also increases blood levels of high-density lipoprotein (HDL) ('good') cholesterol.
Instruction
Use YSP Brozil as directed by your doctor.
Ask your health care provider any questions you may have about how to use YSP Brozil.
Drug interaction
Risk of rhabdomyolysis (muscle injury) increases when gemfibrozil is used with the statin family of cholesterol-reducing medications: pravastatin (Pravachol), lovastatin (Mevacor), rosuvastatin (Crestor), simvastatin (Zocor), fluvastatin (Lescol), and atorvastatin (Lipitor). When this condition is severe it may result in serious kidney damage and death. Concomitant use of these medications is not recommended, symptoms of rhabdomyolysis may appear in three weeks or several months after co-administration. Concomitant use with warfarin increases bleeding and requires correction of warfarin doses. Blood levels of repaglinide (Prandin) are increased by YSP Brozil in patients with diabetes. Cholestyramine (Questran) and Colestipol (Colestid) reduce effects of YSP Brozil when co-administered. YSP Brozil should be administered an hour before or 4-6 hours after intake of cholestyramine or colestipol.