Manufacturer
APOTEX INC
Contents
Clomipramine HCl
Indication
Adjunct for cataplexy associated with narcolepsy, Obsessive compulsive disorder, Panic disorder, Phobias, Depression
Instruction
Should be taken with food.
Drug interaction
Barbiturates increase metabolism of tricyclic antidepressants; conversely cimetidine, guanethidine, haloperidol and phenothiazines block the tricyclic metabolism. CNS effects of alcohol enhanced.
Potentially Fatal: If clomipramine is to be substituted for MAOIs, at least 3 wk should elapse after discontinuing MAOIs. Risk of hypertension and arrhythmias if co-administered with adrenaline and noradrenaline.