Manufacturer
APOTEX INC
Contents
Fluvoxamine maleate
Indication
Depression, Obsessive compulsive disorder
Instruction
May be taken with or without food.
Drug interaction
Increased risk of bleeding with aspirin, NSAIDs, warfarin, ticlopidine, other anticoagulants, atypical antipsychotics and phenothiazines. May increase plasma concentrations of narrow therapeutic index drugs (e.g. theophylline, tacrine, methadone, mexiletine, phenytoin, carbamazepine, ciclosporin), TCAs (e.g. amitriptyline, clomipramine, imipramine), neuroleptics (e.g. clozapine, olanzapine, quetiapine), oxidatively metabolised benzodiazepines (e.g. triazolam, midazolam, alprazolam, diazepam), ropinirole, propranolol, warfarin. Increased risk of hyponatraemia with diuretics.Potentially Fatal: Increased risk of serotonin syndrome with triptans, fentanyl, lithium, tramadol, tryptophan, MAOIs, linezolid, IV methylene blue. May increase serum concentration of pimozide, tizanidine. May increase plasma concentration and risk of QTc prolongation/Torsade de Pointes of terfenadine, astemizole, cisapride, thioridazine.