Manufacturer
ASTRAZENECA AB
Contents
Budesonide
Indication
Bronchial asthma.
Instruction
Respules Adult Initially 1-2 mg bd. Maintenance: 0.5-1 mg bd. Childn Initially 0.5-1 mg bd. Maintenance: 0.25-0.5 mg bd. Turbuhaler Adult 200-800 mcg daily in 2-4 divided inhalations. Severe cases Up to 1,600 mcg. Childn ≥7 yr 100-800 mcg daily in 2-4 divided doses, 5-7 yr 100-400 mcg daily in 2-4 divided doses.
Drug interaction
Increased systemic exposure w/ CYP3A4 inhibitors eg, ketoconazole, itraconazole. Turbuhaler: Increased systemic exposure w/ HIV-PIs. Increased plasma conc & corticosteroid effects w/ oestrogens, contraceptive steroids.