Manufacturer
AstraZeneca Pharmaceuticals LP.
Contents
Saxagliptin HCl
Indication
Adjunct to diet & exercise to improve glycaemic control in patient w/ type 2 DM as monotherapy & as initial combination therapy w/ metformin. Dual oral therapy in combination w/ metformin, a sulphonylurea or thiazolidinedione in patients w/ inadequate glycaemic control. Triple oral therapy in combination w/ metformin & sulphonylurea when diet & exercise do not provide adequate glycaemic control. Combination therapy w/ insulin (w/ or w/o metformin) when diet & exercise do not provide adequate glycaemic control.
Instruction
May be taken with or without food: Do not split/cut tab.
Drug interaction
Increased exposure by ketoconazole. Increased plasma conc w/ strong CYP3A4/5 inhibitors (eg, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, ritonavir, saquinavir, telithromycin).