Manufacturer
ASTRAL PHARM INDUSTRIES
Contents
Amoxicillin Na 1,000 mg, K clavulanate 200 mg
Indication
Short-term treatment for upper & lower resp tract, skin & soft tissue, bone & joint & dental infections, septic abortion, puerperal & intra-abdominal sepsis, septicaemia, peritonitis & post-op infections. Prophylaxis against infections in major surgery.
Instruction
The usual dose is Co-Amoxiclav 1.2g at the induction of anaesthesia. Operations where there is a high risk of infection eg, colorectal surgery, may require 3, and up to 4 doses of Co-Amoxiclav 1.2g in a 24-hr period. These doses are usually given at 0, 8, 16 (and 24) hrs. This regimen can be continued for several days if the procedure has a significantly increased risk of infection.
Drug interaction
Increased & prolonged blood levels w/ probenecid. Increased allergic skin reactions w/ allopurinol. Lowered oestrogen reabsorption & reduced efficacy of combined OCs.