Manufacturer
Aurobindo Pharma Limited (Unit III),
Contents
Venlafaxine
Indication
Depression, Anxiety, Panic disorder
Instruction
Should be taken with food: Take at the same time each day. Swallow whole do not chew/crush/divide/dissolve. Cap may be carefully opened & entire contents sprinkled on a spoonful of applesauce. Swallow drug/food mixt w/o chewing immediately after prep & followed w/ glass of water.
Drug interaction
Increased risk of hyponatraemia with diuretics. Altered glycaemic control of antidiabetic agents (e.g. insulin). Increased risk of QTc prolongation and/or ventricular arrhythmias with concomitant use of other QTc prolonging agents [e.g. class IA and III antiarrhythmics (e.g. quinidine, amiodarone, sotalol, dofetilide), antipsychotics (e.g. thioridazone), macrolides (e.g. erythromycin), quinolone antibiotics (e.g. moxifloxacin)]. Increased serum concentration with CYP3A4 inhibitors (e.g. atazanavir, clarithromycin, itraconazole). Increased serum or plasma concentrations of imipramine metabolite (2-hydroxydesipramine), haloperidol, risperidone, and metoprolol. Decreased serum concentration of indinavir. Increased risk of bleeding with antiplatelet agents (e.g. aspirin), anticoagulants (e.g. warfarin), and NSAIDs.Potentially Fatal: Increased risk of serotonin syndrome with concomitant use of other serotonergic agents (e.g. triptans, SSRIs, SNRIs, amphetamines, lithium, sibutramine, opioids), MAOI (including methylene blue, linezolid), serotonin precursors (e.g. tryptophan), antipsychotics or other dopamine antagonists.
Malaysia
