Manufacturer
BOEHRINGER INGELHEIM PHARMA GMBH & CO.KG
Contents
Repaglinide
Indication
Monotherapy or combination w/ metformin as adjunct to diet & exercise in adult w/ type 2 DM whose hyperglycemia cannot be controlled by diet, wt reduction & exercise.
Instruction
Should be taken with food: Take w/in 30 min before or 15 min after a meal. Patients who skip a meal (or add an extra meal) should be instructed to skip (or add) a dose for that meal.
Drug interaction
CYP2C8 & 3A4 inhibitors. Increased plasma conc w/ ciclosporin. Enhanced &/or prolonged hypoglycaemic effect w/ gemfibrozil, trimethoprim, rifampicin, ketoconazole, itraconazole, clarithromycin, ciclosporin, deferasirox, clopidogrel, other antidiabetics, MAOIs, non-selective β-blockers, ACE inhibitors, salicylates, NSAIDs, octreotide, alcohol, anabolic steroids. Reduced hypoglycaemic effect w/ OCs, rifampicin, barbiturates, carbamazepine, thiazides, corticosteroids, danazol, thyroid hormones, sympathomimetics.
Malaysia
