Manufacturer
Janssen
Contents
Canagliflozin hemihydrate
Indication
Adjunct to diet & exercise to improve glycemic control in adult patient w/ type 2 DM for whom metformin is inappropriate due to contraindications or intolerance. Combination w/ metformin or sulfonylurea in adult patient w/ type 2 DM; combination w/ metformin & either sulfonylurea or pioglitazone in adult patient w/ type 2 DM; as add-on combination therapy w/ insulin (w/ or w/o metformin) in adult patient w/ type 2 DM.
Instruction
May be taken with or without food: Take preferably before the 1st meal of the day.
Drug interaction
Decreased exposure w/ cholestyramine. Add to the effect of diuretics, inulin & insulin secretagogues eg, sulphonylureas; enzyme inducers (eg, St. John's wort, rifampicin, barbiturates, phenytoin, carbamazepine, ritonavir, efavirenz). Increased AUC & Cmax of digoxin.
Malaysia
