Manufacturer
Janssen
Contents
Paliperidone palmitate
Indication
Acute & maintenance treatment of schizophrenia in adults.
Instruction
Adult Initially 150 mg on day 1 & 100 mg 1 wk later by deep IM, followed by subsequent mthly dose of 75 mg. May adjust dose w/in range of 25-150 mg. Mild renal impairment (CrCl ≥50 to <80 mL/min) Initially 100 mg on day 1 & 75 mg 1 wk later, followed w/ mthly dose of 50 mg.
Drug interaction
Centrally acting drugs, alcohol, l-dopa & other dopamine agonists, carbamazepine. Drugs known to prolong QT interval.