Manufacturer
NOVO NORDISK A/S
Contents
Isophane insulin, rDNA
Indication
Treatment of diabetes mellitus.
Instruction
SC Individualized dosage ranging from 0.3-1 IU/kg daily.
Drug interaction
Reduced insulin requirement w/ oral antidiabetics, MAOIs, non-selective β-blockers, ACE inhibitors, salicylates, anabolic steroids, sulphonamides. Increased insulin requirement w/ OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone, danazol. Masked hypoglycaemia symptoms & delayed recovery from hypoglycaemia by β-blockers. Increased or decreased insulin requirement w/ octreotide/lanreotide. Intensified or reduced insulin hypoglycaemic effect by alcohol.