Manufacturer
Novo Nordisk Producao Farmaceutica do Brasil Ltda
Contents
Insulin detemir, rDNA
Indication
DM in adults, adolescents & childn ≥2 yr.
Instruction
May be taken with or without food: For patients treated w/ once daily regimen, administer w/ evening meal or at bedtime. For patients who need bd dosing, the evening dose can be administered either w/ evening meal or at bedtime or 12 hr after morning dose.
Drug interaction
Reduced insulin requirement w/ oral antidiabetics, GLP-1 receptor agonists, MAOIs, β-blockers, ACE inhibitors, salicylates, anabolic steroids, sulphonamides. Increased insulin requirement w/ OCs, thiazides, glucocorticoids, thyroid hormones, sympathomimetics, growth hormone, danazol. Masked hypoglycaemia symptoms by β-blockers. Increased or decreased insulin requirement w/ octreotide/lanreotide. Intensified or reduced hypoglycaemic effect by alcohol.
Malaysia
