Manufacturer
Sandoz Private Limited
Contents
Sildenafil
Indication
Erectile dysfunction, Pulmonary arterial hypertension
Instruction
May be taken with or without food.
Drug interaction
Symptomatic HTN may occur when used w/ alpha-blockers. Reduced clearance w/ CYP3A4 inhibitors (e.g. cimetidine, delavirdine, erythromycin, itraconazole, ketoconazole). Increased plasma concentrations w/ HIV-protease inhibitors particularly by ritonavir-boosted regimens. Decreased plasma concentrations w/ CYP3A4 inducers (e.g. rifampicin, bosentan).
Potentially Fatal: Potentiation of hypotensive effects of nitrates of any form and nicorandil.
Malaysia
