Deskripsi
Manufacturer
SM PHARMACEUTICALS SDN. BHD.
Contents
Glibenclamide
Indication
Type 2 DM.
Instruction
Should be taken with food. Take w/ breakfast or the 1st main meal of the day.
Drug interaction
Serum levels may be reduced by colesevelam. May increase hypoglycaemic effect w/ MAOIs, chloramphenicol, fluoroquinolones (e.g. ciprofloxacin), probenecid, NSAIDs, ACE inhibitors, fluoxetine, disopyramide, clarithromycin, salicylates, sulfonamides, β-blockers. Increased serum levels w/ antifungal antibiotics (e.g. miconazole, fluconazole). May decrease hypoglycaemic effect w/ nonthiazide (e.g. furosemide) and thiazide diuretics, corticosteroids, phenothiazines, thyroid agents, oestrogens, OC, phenytoin, nicotinic acid, sympathomimetic agents, rifampicin, Ca channel blockers, isoniazid.Potentially Fatal: May increase hepatotoxic effect of bosentan.
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