Manufacturer
SM PHARMACEUTICALS SDN. BHD.
Contents
Roxithromycin
Indication
Susceptible infections.
Instruction
Should be taken on an empty stomach. Take at least 15 min before meals.
Drug interaction
Increased risk of cardiovascular adverse effects (e.g. QT prolongation, Torsades de pointes, ventricular arrhythmias) with Class IA and Class III antiarrhythmic agents, terfenadine, astemizole, cisapride, and pimozide. May increased absorption of digoxin and other cardiac glycosides. Increased INR levels with anticoagulants (e.g. warfarin). May increases plasma concentration of theophylline, disopyramide and ciclosporin. May enhance and prolongs effect of midazolam.
Potentially Fatal: Severe vasoconstriction (ergotism) and with possible necrosis of extremities with vasoconstrictive ergot alkaloids (e.g. ergotamine, dihydroergotamine).
Malaysia
