Manufacturer
STADA-VN JOINT VENTURE CO., LTD
Contents
Atorvastatin Ca
Indication
Adjunct to diet for patients w/ elevated total cholesterol, LDL-cholesterol, apolipoprotein B & triglycerides & to increase HDL-cholesterol in patients w/ primary hypercholesterolemia (heterozygous familial & non-familial hypercholesterolemia), combined (mixed) hyperlipidemia (Fredrickson types IIa & IIb), elevated serum triglyceride levels (Fredrickson type IV) & patients w/ dysbetalipoproteinemia (Fredrickson type III) who do not respond adequately to diet. Reduction of total cholesterol & LDL-cholesterol in patients w/ homozygous familial hypercholesterolemia when response to diet & other non-pharmacological measures are inadequate.
Instruction
May be taken with or without food: Avoid excessive consumption (>1 L daily) of grapefruit juice.
Drug interaction
Increased risk of myopathy w/ cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals. Decreased plasma conc w/ oral antacids containing Mg & Al hydroxide & colestipol. Increased digoxin conc. Higher plasma conc w/ erythromycin. Increased AUC values of norethindrone & ethinyl estradiol. Severe myositis & myoglobinuria w/ fibrates.