Manufacturer
Takeda Austria GmbH
Contents
Per cm2 Human fibrinogen 5.5 mg, human thrombin 2 IU
Indication
TachoSil is indicated as an adjunct to haemostasis during surgery when control of bleeding by standard surgical techniques is ineffective or impractical.
Instruction
The use of TachoSil is restricted to experienced surgeons. TachoSil should not be used intravascularly (see Contraindications). For more information on situations where TachoSil should not be used, see Precautions.The number of TachoSil sponges to be applied should always be determined by the underlying clinical need for the patient. The number of TachoSil sponges to be applied vary and should be appropriate to the size of the wound area.Application of TachoSil must be patient-specific and accordingly determined by the treating surgeon. In clinical trials, the individual dosages have typically ranged from 1 to 2 sponges (9.5 cm x 4.8 cm), however application of up to 7 sponges has been reported. For smaller wounds, e.g. in minimal invasive surgery, the smaller sized sponges (4.8 cm x 4.8 cm or 3.0 cm x 2.5 cm) are recommended.
Drug interaction
No formal interaction studies have been performed. Similar to comparable products or thrombin solutions, TachoSil may be denatured after exposure to solutions containing alcohol, iodine or heavy metals (e.g. antiseptic solutions). Such substances should be removed to the greatest possible extent before application of TachoSil.
Malaysia
