Manufacturer
XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
Contents
Atropine
Indication
Mydriasis and cycloplegia for refraction, Iritis, Uveitis.
Instruction
Mydriasis and cycloplegia for refraction
Adult: As 1% solution: Instill 1-2 drop(s) in the conjunctiva 40 minutes to 1 hour prior to procedure. May be repeated bid as necessary. As 1% ointment: Apply 0.3-0.5 cm into the conjunctival sac up to 3 times daily.
Child: As 1% solution: Instill 1 drop into each eye bid for 1-3 days prior to procedure. As 1% ointment: Apply 0.3 cm into the conjunctival sac up to thrice daily for 1-3 days before the procedure.
Iritis, Uveitis
Adult: As 1% solution: Instill 1-2 drop(s) into the eye up to 4 times daily.
Child: As 1% solution: Instill 1 drop into each eye up to 3 times daily.
Drug interaction
Additive antimuscarinic effect with amantadine, antiarrhythmics (e.g. disopyramide, quinidine), anticholinergics, TCA, MAOIs, antipsychotics (e.g. phenothiazine, clozapine, haloperidol), antiparkinsonian drugs, antispasmodics (e.g. domperidone), and some antihistamines (e.g. promethazine). Reduces absorption of ketoconazole and mexiletine. Antagonises therapeutic effects of synthetic choline esters (e.g. bethanechol, carbachol), anticholinesterase drugs (e.g. physostigmine, neostigmine, pyridostigmine), and cholinomimetic alkaloids (e.g. pilocarpine). May increase risk of severe constipation with opioid analgesics. Antagonises miotic actions of ophthalmic long-acting cholinergic antiglaucoma agents (e.g. echothiopate). May increase toxic effects of antimyasthenics, K citrate, K supplements. May antagonise gastrointestinal motility effects of cisapride, domperidone and metoclopramide.
Malaysia
