Manufacturer
Servier
Contents
Gliclazide
Indication
NIDDM associated w/ an adapted diet in cases where dietary measures alone provide inadequate to control of blood glucose levels.
Instruction
Should be taken with food: Take immediately before meals.
Drug interaction
Increased hypoglycaemic effect w/ miconazole (systemic route, oromucosal gel); phenylbutazone (systemic route), alcohol. Potentiated blood glucose lowering effect w/ other antidiabetic agents (insulins, acarbose, metformin, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, GLP-1 receptor agonists), β-blockers, fluconazole, ACE inhibitors (captopril, enalapril), H2-receptor agonists, MAOIs, sulfonamides, clarithromycin & NSAIDs. Diabetogenic effect of danazol. Increased blood glucose levels w/ chlorpromazine, glucocorticoids, ritodrine, salbutamol, terbutaline. Decreased exposure by St. John's wort. Risk of dysglycaemia w/ fluoroquinolones. Potentiated anticoagulation w/ warfarin.