Manufacturer
KOTRA PHARMA (M) SDN. BHD.
Contents
Aspirin
Indication
Fever, Mild to moderate pain, Acute ischaemic stroke, Angina pectoris, Myocardial infarction, Rheumatic disorders, Prophylaxis of cardiovascular events in high-risk patients
Instruction
Should be taken with food.
Drug interaction
Increased risk of GI bleeding and ulceration with corticosteroids. Increased risk of bleeding with coumarin anticoagulants (e.g. heparin, warfarin, phenindione) and antiplatelet agents (e.g. clopidogrel, dipyridamole). May result in severe acidosis and increased CNS toxicity with carbonic anhydrase inhibitors (e.g. acetazolamide). Increases the hypoglycaemic effect of sulfonylureas. Reduces binding of phenytoin and valproate to serum albumin leading to increased free concentration of the drugs. Reduces the effect of uricosurics (e.g. probenecid, sulfinpyrazone). Impairs the renal excretion of lithium and digoxin.Potentially Fatal: Increased risk of GI bleeding and ulceration with other NSAIDs. Increased risk of haematological toxicity of methotrexate.