Relvar Ellipta 200/25 Micrograms Inhalation Powder, Pre-Dispensed

Manufacturer
GLAXO OPERATIONS UK LTD
 
Contents
200/25 mcg inhalation Fluticasone furoate 200 mcg, vilanterol trifenatate 25 mcg, predispensed (delivered dose of fluticasone furoate 184 mcg, vilanterol trifenatate 22 mcg)
 
Indication
Regular treatment of asthma in adult & adolescent ≥12 yr & not adequately controlled w/ inhaled corticosteroid & ''as needed'' inhaled short-acting β₂-agonist. 100/25 mcg inhalation Symptomatic treatment of adult w/ COPD w/ FEV₁ <70% predicted normal w/ an exacerbation history despite regular bronchodilator therapy.
 
Instruction
Asthma Adult & adolescent ≥12 yr 1 inhalation of 100/25 mcg once daily, may be increased up to max 200/25 mcg once daily. COPD Adult ≥18 yr 1 inhalation of 100/25 mcg once daily.
 
Drug interaction
Weakened or antagonized effect by β₂-adrenergic blockers. Increased systemic exposure w/ CYP3A4 inhibitors eg, ketoconazole, ritonavir. Potentiated AR w/ other sympathomimetic drugs.