Manufacturer
GLAXOSMITHKLINE BIOLOGICALS S.A
Contents
Each dose (0.5 mL) of cloudy, white, sterile suspension contains not less than 2.5 Lf of diphtheria toxoid, not less than 5 Lf (20 IU) of tetanus toxoid; 8 μg of pertussis toxoid, 8 μg of filamentous haemagglutinin, 2.5 μg of pertactin (69 kDa outer membrane protein), 40 D-antigen units (DU) of Type 1 poliovirus, 8 DU of Type 2 polio virus and 32 DU Type 3 polio virus. Nonmedicinal ingredients: medium 199 (as stabilizer containing amino acids, mineral salts, vitamin and other substances), sodium chloride, water for injection. Formaldehyde, neomycin, and polymycin are present as traces.
Indication
It is used to prevent pertussis (whooping cough), diphtheria, tetanus, and poliomyelitis (polio).
Instruction
The usual dose of this vaccine is 0.5 mL given as an injection into the muscle of the upper outer arm in children 4 years of age and older, adolescents, and adults who have been previously vaccinated against pertussis, diphtheria, polio and tetanus.This vaccine is given by a health care professional in a doctor's office or clinic.
Drug interaction
There may be an interaction between the pertussis - diphtheria toxoid - tetanus toxoid - poliomyelitis vaccine and any of the following: acetaminophen, belimumab, fingolimod, immunosuppressants (medications used to treat cancer or autoimmune disease, or prevent organ rejection), azathioprine,corticosteroids (e.g., budesonide, dexamethasone, hydrocortisone, fluticasone,prednisone) cyclosporine, hydroxyurea, infliximab medications to treat cancer (e.g., carboplatin, cyclophosphamide, doxorubicin, ifosfamide, vincristine) mycophenolate, rituximab, tacrolimus, warfarin.
Malaysia
