Zantac Injection 50mg/2ml

Manufacturer
GlaxoSmithKline Manufacturing S.p.A
 
Contents
Ranitidine HCl
 
Indication
Prophylaxis of Mendelson's Syndrome, Prophylaxis of Haemorrhage from Stress Ulceration in Seriously Ill Patients or Prophylaxis of Recurrent Haemorrhage in Patients Bleeding from Peptic Ulceration, Prophylaxis of Stress Ulceration in Seriously Ill Patients: Patients over 50 years of age.
 
Instruction
Prophylaxis of haemorrhage from stress ulceration in seriously ill patient or recurrent haemorrhage in patient bleeding from peptic ulceration 150 mg bd. Inj 50 mg slow IV every 6-8 hr; 25 mg/hr intermittent IV infusion for 2 hr, repeated every 6-8 hr interval or 50 mg IM every 6-8 hr. Prophylaxis of Mendelson's syndrome 50 mg IM or slow IV inj 45-60 min before general anaesth induction. Prophylaxis of upper GI haemorrhage from stress ulceration in seriously ill patient 50 mg slow IV as priming dose, followed by 0.125-0.25 mg/kg/hr continuous IV infusion.
 
Drug interaction
Altered prothrombin time w/ coumarin anticoagulants eg, warfarin. Increased plasma levels of procainamide & N-acetylprocainamide. Increased absorption of triazolam, midazolam, glipizide. Decreased absorption of ketoconazole, atazanavir, delaviridine, gefitnib. Reduced absorption by high-dose sucralfate.