Manufacturer
PFIZER (PERTH) PTY. LTD.
Contents
Cytarabine
Indication
Induction & maintenance of remission in acute myelocytic leukaemia in adult & childn. Other leukemias eg, acute lymphocytic leukaemia, chronic myelocytic leukaemia (blast phase).
Instruction
Administered by intravenous injection or infusion, or subcutaneously. It has been administered intrathecally as a special application.
Drug interaction
Reduced effectiveness of methotrexate. Decreased steady-state plasma digoxin conc w/ β-acetyldigoxin & chemotherapy regimens containing cyclophosphamide, vincristine & prednisone w/ or w/o cytarabine or procarbazine. Antagonised K pneumoniae strains w/ gentamicin. Potential competitive inhibition uptake of fluorocytosine.