Manufacturer
PFIZER AUSTRALIA PTY. LTD.
Contents
Sildenafil citrate
Indication
Erectile dysfunction.
Instruction
May be taken with or without food. Adult 50 mg once daily as needed, taken approx 1 hr before sexual activity, may be increased to 100 mg or decreased to 25 mg. Max daily dose: 100 mg. Hepatic & severe renal impairment 25 mg once daily.
Drug interaction
Reduced clearance w/ CYP3A4 inhibitors eg, ketoconazole, erythromycin, cimetidine. Increased AUC & Cmax of bosentan. Decreased plasma conc by strong CYP3A4 inducers eg, rifampin. Potentiated hypotensive effects of nitric oxide, organic nitrates & nitrites. Symptomatic hypotension w/ α-blockers eg, doxazosin.
Malaysia
