Manufacturer
PFIZER (PERTH) PTY. LTD.
Contents
Lignocaine 2%, chlorhexidine 0.05%
Indication
local anaesthesia and lubrication during catheterisation, exploration by sound and other endourethral
operations and examinations.Cystoscopy and symptomatic treatment of painful cystitis and urethritis.
Instruction
Males: The usual dose required for adequate analgesia is 20 mL (equiv. lignocaine 400 mg).
The gel is instilled slowly into the urethra until it reaches the external sphincter, proximal to the
prostate, where a certain resistance is felt. Compression is then applied for several minutes at the
corona. The remaining gel is administered, filling the length of the urethra.
For procedures such as sounding or cystoscopy, a larger quantity of gel (up to 40 mL) may be
required. This amount should be instilled in three to four portions and anaesthesia allowed to take
effect for five to ten minutes before insertion of the instrument.
Females: Instil 5 to 10 mL in small portions to fill the whole urethra. In order to obtain adequate
anaesthesia, three to five minutes should be allowed prior to performing urological procedures. Children: In children under the age of 12 years up to 6mg/kg can be used.
Drug interaction
Cimetidine has been shown to reduce clearance of IV administered lignocaine. Caution should be taken if administered concurrently with lignocaine. Antiarrhythmic drugs: Lignocaine should be used with caution in patients receiving antiarrhythmic drugs such as mexiletine, since the toxic effects are additive. Antiepileptic drugs: Phenytoin and other antiepileptic drugs such as phenobarbitone, primidone and carbamazepine appear to enhance the metabolism of lignocaine but the significance of this effect is not known. Phenytoin and lignocaine have additive cardiac depressant effects.
Malaysia
