Manufacturer
PHARMANIAGA MANUFACTURING BERHAD
Contents
Methyldopa
Indication
Hypertension
Instruction
May be taken with or without food.
Drug interaction
Potentiation of hypotensive effects w/ diuretics and other antihypertensives. Reduced metabolism w/ COMT inhibitors (e.g. entacapone). Sympathomimetics may antagonise the hypotensive effects of methyldopa. Paradoxical antagonism of hypotensive effects w/ TCAs, antipsychotics and β-blockers. May increase lithium toxicity. Potentially Fatal: Diminished hypotensive effect w/ MAOIs.