Manufacturer
PHARMANIAGA MANUFACTURING BERHAD
Contents
Diphenoxylate HCl 2.5 mg, atropine sulfate 25 mcg
Indication
Diarrhoea.
Instruction
May be taken with or without food.
Drug interaction
Increased antimuscarinic side effects w/ amantadine, antihistamines, and TCAs. Antagonises the effect of domperidone, metoclopramide, bethanechol, carbachol, cisapride, galantamine, neostigomine, pyridostigmine, and pilocarpine. May potentiate CNS depressant effects of barbiturates and tranquilizers. May precipitate hypertensive crisis when concomitantly used w/ MAOIs. May reduce absorption of ketoconazole. May reduce plasma concentration of levodopa. Increased effect w/ memantine.