Manufacturer
PHARMANIAGA LIFESCIENCE SDN. BHD.
Contents
Labetalol HCl
Indication
Severe HTN in pregnancy. Hypotensive anaesth. Hypertensive episodes following acute MI.
Instruction
Severe HTN in pregnancy Initially 20 mg/hr then doubled every 30 min until satisfactory response is obtained or 160 mg/hr is reached. HTN due to other causes 2 mg/min until satisfactory response is obtained. Dose range: 50-200 mg. Hypotensive anaesth Initially 10-20 mg IV, may be increased in 5-10 mg increments until desired BP level is attained. Hypertensive episodes following acute MI Initially 15 mg/hr, gradually increased to max: 120 mg/hr.
Drug interaction
Enhanced hypotensive effects of halothane. Reduced hypotensive effect w/ NSAIDs. Reduced uptake of metaiodobenzylguanidine radioisotopes. Enhanced digoxin effect in reducing ventricular rate. Bradycardia & HTN w/ adrenaline. Class I antiarrhythmics or verapamil-type Ca antagonists. Interfered w/ certain fluorescent substances assay. Falsely elevated urinary catecholamine levels.