Manufacturer
PHARMANIAGA LIFESCIENCE SDN. BHD.
Contents
Dopamine HCl
Indication
Acute heart failure
Instruction
Adult: For correction of haemodynamic imbalance as present in shock, MI, open heart surgery, renal failure, or cardiac decompensation: Initially, 2-5 mcg/kg/minute, increased gradually by up to 5-10 mcg/kg/minute according to patient's blood pressure, cardiac and urine output. For severe cases, up to 20-50 mcg/kg/minute may be required.
Drug interaction
Cardiac effects are antagonised by β-adrenergic agents (e.g. propanolol, metoprolol). α-adrenergic blocking agents may antagonise the vasoconstricting effect of high dose dopamine. Prolonged and enhanced effect with MAOIs. Risk of hypotension and bradycardia with phenytoin. May enhance effect of diuretics. Risk of excessive vasoconstriction with ergot alkaloids. May enhance vasopressor effect with TCAs and guanethidine.Potentially Fatal: May enhance the arrhythmogenic effect with cyclopropane and halogenated hydrocarbon anaesthetics.
Malaysia
