Manufacturer
DUOPHARMA MANUFACTURING (BANGI) SDN BHD
Contents
Losartan
Indication
Hypertension, Diabetic nephropathy in Type 2 diabetes mellitus and Heart failure.
Instruction
May be taken with or without food.
Drug interaction
May potentiate hypotensive effect with other antihypertensive agents. May increase risk of hypotension as an adverse reaction of antipsychotics and amifostine. Decreased plasma concentration with rifampicin and fluconazole. Increased serum K levels and enhance hyperkalaemic effect with K-sparing diuretics (e.g. amiloride, spironolactone), K supplements or K-containing salt substitutes (e.g. heparin). May increase serum lithium concentrations and toxicity. May increase risk of renal impairment and may decrease hypotensive effect with NSAIDs.Potentially Fatal: Increased risk of hypotension, hyperkalaemia, and nephrotoxicity with ACE-inhibitors or aliskiren.