Manufacturer
Hetero Labs
Contents
Quetiapine fumarate
Indication
Schizophrenia. Depressive & acute manic episodes associated w/ bipolar I disorder as either monotherapy or adjunct to lithium or divalproex. Maintenance treatment of bipolar I disorder as adjunct therapy to lithium or divalproex. Prevention of recurrence in patients w/ bipolar disorder & whose manic or depressive episode has responded to quetiapine treatment.
Instruction
May be taken with or without food: Swallow whole, do not split/chew/crush.
Drug interaction
Decreased plasma conc w/ strong hepatic enzyme inducer eg, carbamazepine or phenytoin. Increased AUC w/ ketoconazole. Increased clearance w/ thioridazine. Concomitant use w/ other centrally acting drugs, alcohol, drugs causing electrolyte imbalance or increased QTc interval. Not recommended w/ grapefruit juice.