Manufacturer
NOVARTIS SAGLIK
Contents
Artemether 20 mg, lumefantrine 120 mg
Indication
Acute uncomplicated falciparum malaria,
Instruction
Should be taken with food.
Drug interaction
May reduce effectiveness of hormonal contraceptives.Potentially Fatal: Decreased plasma concentration with strong CYP3A4 inducers (e.g. phenytoin, carbamazepine, rifampicin). Additive QT prolongation effect with antiarrhythmics Class I and II (e.g. quinidine, amiodarone), antipsychotics (e.g. pimozide, ziprasidone), neuroleptics, antidepressants, antibiotics (e.g. macrolide, fluoroquinolone), triazole antifungals, non-sedating antihistamines (e.g. terfenadine, astemizole), cisapride, flecainide, halofrantine.