Manufacturer
PHARMANIAGA MANUFACTURING BERHAD
Contents
Simvastatin
Indication
In CHD, to reduce risk of death, coronary death & non-fatal MI, reduce risk for undergoing myocardial revascularisation procedures & slow progression of coronary atherosclerosis, reduce development of new lesions & new total occlusions. Adjunct to diet in patients w/ primary hypercholesterolaemia, heterozygous familial hypercholesterolaemia or mixed hyperlipidaemia when response to diet & other non-pharmacological measures is inadequate.
Instruction
May be taken with or without food: Avoid excessive consumption (>1 L daily) of grapefruit juice.
Drug interaction
Immunosuppressants, gemfibrozil, lipid-lowering doses of nicotinic acid, macrolides, cholestyramine, colestipol, coumarin anticoagulants, azole antifungals, HIV PIs, nefazodone.
Malaysia
