Constant late nights, over-fatigue as well as over-consumption of alcohol and cold drinks can cause the backbone to ache and weak limbs. In serious cases, loss of sperm, spermatorrhea, uncontrolled urination, loosening of muscles, mental illness and mental fatigue may occur. Take Tonicap from Conforer to effectively nourish the kidneys, replenish energy, contract muscles and relieve fatigue.