Manufacturer
Sanofi
Contents
Sulpiride
Indication
Acute & chronic psychotic disorders (schizophrenia, nonschizophrenic chronic delusions: Paranoiac delusion, chronic psychoses w/ hallucination). Severe behavioral disorders (agitation, self-mutilation, stereotyping) in children >6 year, particularly in the context of autistic syndromes. Short-term treatment of the symptoms of anxiety in adult if standard therapies have failed.
Instruction
May be taken with or without food.
Drug interaction
Combination with bradycardia-inducing medications (e.g. β-blockers, some Ca channel blockers) or medications which induce electrolyte imbalance (e.g. hypokalaemic diuretics, stimulant laxatives, IV amphotericin B, glucocorticoids, tetracosactides) may induce torsades de pointes or prolong the QT interval. Enhanced postural hypotension if used w/ other antihypertensive drugs. Concurrent use w/ other CNS depressants may cause increased CNS depression. Co-admin w/ antacids or sucralfate may decrease sulpiride absorption. Concurrent use w/ lithium increases the risk of extrapyramidal side effects. May reduce effectiveness of ropinorole.
Potentially Fatal: Reciprocal antagonism of effects between levodopa and neuroleptics.
Malaysia
