Manufacturer
Abbott
Contents
14 white FC tab each containing Estradiol 1 mg, 14 grey FC tab each containing Estradiol 1 mg, dydrogesterone 10 mg
Indication
Hormone replacement therapy for women with disorders due to natural or surgically induced menopause with intact uteri.
Instruction
Take 1 white tab daily for 1st 14 days, followed by 1 grey tab daily for the next 14 days without interruption. If patient is still menstruating, begin treatment on the 1st day after onset of menstruation.
Drug interaction
Reduced estrogen effect w/ liver enzyme inducers eg, oxcarbazepine, topiramate, felbamate, barbiturates, phenytoin, rifampicin, carbamazepine. Femoston increased metabolism by anticonvulsants eg, phenobarbital, carbamazepine, phenytoin & anti-infectives eg, rifampicin, rifabutin, nevirapine, efavirenz. Exhibit inducing properties w/ ritonavir & nelfinavir. Induced metabolism w/ herbal prep containing St. John's wort (Hypericum perforatum). Interfered metabolism of tacrolimus & cyclosporine A, fentanyl, theophylline.
Malaysia
