Manufacturer
GlaxoSmithKline
Contents
Isosorbide dinitrate
Indication
Acute angina
Instruction
1-3 sprays (1.25 mg/spray) directed under the tongue.
Drug interaction
Increased hypotensive effects with alcohol or vasodilators. Marked orthostatic hypotension may occur when used with calcium channel blockers. Vasodilatory effect may be reduced with dihydroergotamine. Ergotamine effects may be enhanced. Reduced effectiveness of sublingual form with disopyramide.
Potentially Fatal: Significant hypotension may occur with phosphodiesterase-5 inhibitors.
Malaysia
