Manufacturer
ORION CORP
Contents
Verapamil HCl
Indication
Supraventricular arrhythmias
Instruction
5-10 mg via slow inj over 2-3 minutes then 5 mg via inj after 5-10 minutes if needed.
Drug interaction
May increase plasma level w/ CYP3A4 inhibitors (e.g. erythromycin, ritonavir), cimetidine. May decrease plasma level w/ CYP3A4 inducers (e.g. rifampicin), phenobarbital, sulfinpyrazone. Increased risk of bleeding w/ aspirin. May increase bradycardic and hypotensive effect w/ telithromycin. Increased AV blocking effect w/ clonidine. May increase plasma level of cardiac glycosides (e.g. digoxin, digitoxin), β-blockers (e.g. propranolol, metoprolol), α-blockers (e.g. terazosin, prazosin), immunosuppressants (e.g. sirolimus, ciclosporin, tacrolimus, everolimus), lipid lowering agents (e.g. lovastatin, simvastatin, atorvastatin), colchicines, quinidine, carbamazepine, imipramine, glibenclamide, doxorubicin, midazolam, buspirone, almotriptan, theophylline. May potentiate hypotensive effect w/ diuretics, antihypertensives, vasodilators. May increase neurotoxic effect of lithium.
Malaysia
