Tisseel, [Fibrin Sealant] Frozen Solution

Manufacturer
Baxter AG
 
Contents
Per mL of component 1 Human fibrinogen 91 mg, aprotinin 3,000 KIU. Per mL of component 2 Human thrombin 500 IU, Ca chloride 40 micromol
 
Indication
Hemostasis improvement; tissue glue to improve wound healing or to support sutures in vascular surgery & GI anastomoses; tissue sealing to improve adhesion of the separated tissue eg, tissue flaps, grafts, split skin grafts (mesh grafts).
 
Instruction
Individualized dosage ranging from 4-20 mL. Surfaces gluing 2 mL for at least 10 cm² area.
 
Drug interaction
Denaturation after exposure to soln containing alcohol, iodine or heavy metals (eg, antiseptic soln).