Prontosan® contains betaine and polihexanide. Betaine reduces the environmental surface tension of the biofilm which results in a maceration of the biofilm and finally allows a better penetration into it. The mechanism of action can basically be compared with a dishwashing detergent. Polihexanide is an antimicrobial agent with broad specturm biocidal activity. The mode of action can be described as a non-specific electrostatic interaction with the bacterial cell wall. The attachment of polihexinde to the bacterial cell wall results in a disorganisation of the biological structure of the bacteria.
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