TSH Rapid Test Cassette（WB/S/P）

【SUMMARY】
Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, TSH, or hTSH for human TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4 ), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid. TSH (with a half life of about an hour) stimulates the thyroid gland to secrete the hormone thyroxine (T4), which has only a slight effect on metabolism. T4 is converted to triiodothyronine (T3), which is the active hormone that stimulates metabolism. About 80% of this conversion is in the liver and other organs, and 20% in the thyroid itself. Laboratory testing of thyroid stimulating hormone* levels in the blood is considered the best initial test for hypothyroidism. * TSH It is important to note the statement from the Subclinical Thyroid Disease Consensus Panel: “There is no single level of serum TSH at which clinical action is always either indicated or contraindicated. The higher the TSH, the more compelling is the rationale for treatment. It is important to consider the individual clinical context (e.g. pregnancy, lipid profile, ATPO antibodies),” The TSH Rapid Test Cassette (Whole Blood/Serum/Plasma) is a rapid test that qualitatively detects the presence of TSH in whole Blood, serum or plasma specimen at the sensitivity of 5μlU/ml. The TSH Rapid Test Cassette (Whole Blood/Serum/Plasma) is a simple test that utilizes a combination of monoclonal antibodies to selectively detect elevated levels of TSH in whole blood, serum or plasma.

【DIRECTIONS FOR USE】
Allow the test, specimen, buffer and/or controls to reach room temperature (15-30°C) prior to testing.
1. Bring the pouch to room temperature before opening it. Remove the test cassette from the sealed pouch and use it as soon as possible.
2. Place the cassette on a clean and level surface.
For Serum or Plasma specimen:
· Hold the dropper vertically and transfer 1 drop of serum or plasma (approximately 25μL) to the specimen well then add 1 drop of buffer (approximately 40μL), and start the timer.
See illustration below.
For Venipuncture Whole Blood specimen:
· Hold the dropper vertically and transfer 2 drops of whole blood (approximately 50μL) to the specimen well, then add 1 drop of buffer (approximately 40μL), and start the timer. See illustration below.
For Fingerstick Whole Blood specimen:
· To use a capillary tube: Fill the capillary tube and transfer approximately 50μL of fingerstick whole blood specimen to the specimen area of test cassette, then add 1 drop of buffer (approximately 40μL) and start the timer. See illustration below.
· To use hanging drops: Allow 2 hanging drops of fingerstick whole blood specimen (approximately 50μL) to fall into the specimen area of test cassette, then add 1 drop of buffer (approximately 40μL) and start the timer. See illustration below.
3. Wait for the colored line(s) to appear. Read results at 10 minutes. Do not interpret the result after 20 minutes.