Manufacturer
NOVO NORDISK A/S
Contents
Biosynthetic human somatropin
Instruction
Adult onset GHD Initially 0.1-0.3 mg daily. Max maintenance dose: 1 mg daily. Childhood onset GHD Restart w/ 0.2-0.5 mg daily dose.Children GHD 0.025-0.035 mg/kg or 0.7-1 mg/m2 daily. Turner syndrome 0.045-0.067 mg/kg or 1.3-2 mg/m2 daily. Chronic renal disease 0.05 mg/kg or 1.4 mg/m2 daily. Born SGA 0.033-0.067 mg/kg or 1-2 mg/m2 daily.
Drug interaction
Inhibited growth promoting effect by glucocorticoids. Increased clearance of sex steroids, corticosteroids, anticonvulsants, cyclosporine. Influenced effect by gonadotropin, anabolic steroids, estrogens, thyroid hormone.
Malaysia
