Manufacturer
XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
Contents
Hyoscine-N-butylbromide
Indication
Gastrointestinal tract spasm, Genitourinary spasm, Prophylaxis of motion sickness, IBS (irritable bowel syndrome),
Instruction
Gastrointestinal tract spasm, Genitourinary spasm
Adult: As hyoscine butylbromide: 20 mg 4 times daily.
Child: As hyoscine butylbromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose.
Prophylaxis of motion sickness
Adult: As hyoscine hydrobromide: Initially, 0.15-0.3 mg 20-30 minutes before a journey, repeat 6 hourly if needed, up to max 3 doses in 24 hours. Max: 0.9 mg daily.
Child: As hyoscine hydrobromide: 3-4 years Initially, 0.075 mg, repeated once if needed. Max: 0.15 mg daily; >4-10 years 0.075-0.15 mg, repeat 6 hourly if needed. Max: 0.45 mg daily; >10 years 0.15-0.30 mg, repeat 6 hourly if needed. Max: 0.9 mg daily. All doses should be given 20-30 minutes before a journey.
IBS (irritable bowel syndrome)
Adult: As hyoscine butylbromide: Initially, 10 mg tid, may increase up to 20 mg 4 times daily if needed.
Child: As hyoscine butylbromide: 6-11 years 10 mg tid; ≥12 years Same as adult dose.
Drug interaction
May decrease the absorption of oral medicines due to decreased gastric motility and delayed gastric emptying. The sedative effect of hyoscine may be enhanced by other CNS depressants. Other drugs with anticholinergic properties (e.g. amantadine, antihistamines) may enhance the effects of hyoscine.
Malaysia
